Abstract
IntroductionInfective endocarditis (IE) is a life-threatening illness with a high morbidity and mortality, and with a rise in incidence in patients with prosthetic valves and cardiac devices. Recently the Dutch guidelines of IE prophylaxis have been revised, limiting IE prophylaxis to the highest-risk population. The aim of the present study was to investigate the incidence of IE and its trend between 2008–2013 in a regional hospital in the Netherlands.MethodsThis is an observational descriptive study of all patients who were admitted with IE to the Medical Center of Alkmaar (MCA) from 1 January 2008 to 31 December 2013.ResultsA total of 89 patients with IE, including 7 patients (7.9 %) with a cardiac device IE (CDIE), were identified. In 2008 there were 8 patients with IE, this increased to 26 patients in 2013. Patients with a prosthetic valve IE increased from 25 % in 2008 to 34.6 % in 2013. This increase was not seen in patients with CDIE.ConclusionIn the MCA we have observed an increase in patients with IE since 2010. This increase was in part attributable to prosthetic valve IE. A larger observational study is needed to investigate the increase of IE in the Netherlands.
Highlights
Infective endocarditis (IE) is a life-threatening illness with a high morbidity and mortality, and with a rise in incidence in patients with prosthetic valves and cardiac devices
The aim of the study was to investigate if there was an increase in incidence of IE in the Medical Center of Alkmaar (MCA) between 2008 and 2013
We observed an increase in incidence of IE especially in the last 3 years. This increase is in part attributable to patients with a prosthetic valve
Summary
Infective endocarditis (IE) is a life-threatening illness with a high morbidity and mortality, and with a rise in incidence in patients with prosthetic valves and cardiac devices. Patients with a prosthetic valve IE increased from 25 % in 2008 to 34.6 % in 2013 This increase was not seen in patients with CDIE. Conclusion In the MCA we have observed an increase in patients with IE since 2010 This increase was in part attributable to prosthetic valve IE. A larger observational study is needed to investigate the increase of IE in the Netherlands. In the past IE was a disease that commonly affected patients with predisposing valvular abnormalities caused by rheumatic carditis [2] This presentation is currently typically seen in developing countries. IE is not a uniform disease and it is evolving with changes in its microbiological profile due to a higher incidence of healthcare-associated procedures in elderly patients [11]
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