Abstract
Introduction. Chronic non-communicable diseases (CNCDs) remain the most important medical and social problem and cause significant damage to the economy of the capital. In this situation prevention, early detection and timely treatment of diseases among the working-age population are of particular importance. In an urban environment, a person is constantly exposed to the following risk factors that negatively affect health: reduced physical activity and a sedentary lifestyle, high levels of stress, poor nutrition. The latter is also one of the reasons for the increase in the incidence of obesity and diabetes mellitus type 2 (hereinafter – DM2) and the prevalence of metabolic syndrome (hereinafter – MS). The purpose of the study was to assess the level and dynamics of the incidence of the working-age population of the city of Moscow by the class of endocrine diseases, DM2 and obesity in the administrative districts.
 Materials and methods. For the analysis data from medical organizations of the Moscow City Health
 Department on registered morbidity for 2017–2021 were taken. The method of direct ranking was used, the calculation of indicators of the dynamic series.
 Results. For the study period 2017–2021 in the city of Moscow, the overall morbidity rate of the workingage population in the endocrine diseases class increased by 36.4 %, DM2 – by 17 %, obesity – by 38,3 %. The primary morbidity rate of the working-age population in the endocrine diseases class decreased by 5,1%, DM 2 – by 24,7 %, obesity – by 45,9 %.
 The rates of general morbidity in the class of endocrine diseases and DM 2 decreased most rapidly in the Zelenograd administrative district (ZelAO) - 13.3% and 18%, respectively, and obesity – in the South-Western administrative district (SWAO) by 23.3%. The decrease in primary morbidity in the endocrine diseases class was most rapidly recorded in the North-Western Administrative District (NWAO) – by 36 %, DM 2 in the Eastern Administrative District (EAO) – by 50.4 %, obesity in the Troitsky and Novomoskovsk administrative districts
 (TiNAO) – by 83 %.
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