Abstract

IntroductionCardiorespiratory fitness (CRF) is a strong independent predictor of cardiovascular disease (CVD) and CVD mortality. However, little is known in regards to how CRF has trended in apparently healthy adults over the past several decades.PurposeTo analyze trends in CRF and CVD risk factors over the last 50 years in a population of apparently healthy adult men and women.MethodsParticipants were 4,214 apparently healthy adults (2,390 men and 1,824 women) from the Ball State Adult Fitness Longitudinal Lifestyle STudy (BALL ST) that performed maximal cardiopulmonary exercise testing between 1970–2019 for the assessment of CRF defined as VO2max (ml/kg/min). Participants were self-referred either to a community-based exercise program, fitness testing, or were research subjects in exercise related studies and were placed into groups by decade based on testing date.ResultsCRF showed a general trend to decline (P<0.05) from the 1970s to the 2000s with an increase (P<0.05) from the 2000s to the 2010s for both men and women. This pattern persisted for age and sex-adjusted CRF level, determined by Fitness Registry and the Importance of Exercise: A National Data Base (FRIEND). For both women and men, CRF across the decades was associated (P<0.05) with the prevalence of physical inactivity, smoking, obesity, dyslipidemia and hypertension, and with diabetes in men only.ConclusionCRF declined from 1970 through the 2000s in a cohort of apparently healthy men and women which was associated with worsening CVD risk profiles. However, the decline in CRF was attenuated over the past decade which may have a positive impact on future CVD in the population. Promoting physical activity to increase CRF should be a primary aspect of CVD prevention programs.

Highlights

  • Cardiorespiratory fitness (CRF) is a strong independent predictor of cardiovascular disease (CVD) and CVD mortality

  • The decline in CRF was attenuated over the past decade which may have a positive impact on future CVD in the population

  • While CRF was initially investigated for its relation with human performance, over the past 30 years CRF has been established as a powerful determinant of cardiovascular disease (CVD) and CVD-mortality that is independent of traditional risk factors [1,2,3,4]

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Summary

Objectives

The primary objective of the current study was to examine cross-sectional trends in CPET-derived CRF in apparently healthy adult men and women over the past five decades. The primary purpose of this study was to assess trends in directly-measured CRF over the past 50 years (1970–2019) in apparently healthy adult men and women from the BALL ST cohort

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