Abstract
Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staff capacity building and increasing public awareness.
Highlights
Tuberculosis [TB] remains major Public health problem and among the top ten leading causes of human deaths worldwide
Pulmonary TB, smear positive (SPPTB): SPPTB case is based on the presence of at least one acid fast bacillus (AFB+) in at least one sputum sample in countries with a well-functioning EQA system
Among 506 TB patients registered in DOTS clinic in the DebreBerhan referral hospital, almost half of the patients are smear negative pulmonary tuberculosis 255 (50.4%); where as two out of five patients (37.2%) are smear positive pulmonary tuberculosis and the remaining are extra pulmonary TB 63(12.5%)
Summary
Tuberculosis [TB] remains major Public health problem and among the top ten leading causes of human deaths worldwide. 71.8 in 2006/07, TB treatment success rate improved from the base line 85 to 90.6 and TB cure rate from the baseline 69.0% in 2006/07 to 91 in 2013, and reduce the mortality rate by 50 % [2]. The country Still ranks second in Africa after Nigeria and seventh among the world’s 22 high TB burden countries with estimated TB prevalence rate of 227/1000000 population , 18 TB deaths and with an estimated incidence rate of 224 per 100,000 populations respectively [3]. Low income, no or limited access to transport, distance from home to the Tsegahun Asfaw et al.: Trends and Treatment Outcomes of Tuberculosis in Debre Berhan. This study is designed to assess trend of TB and treatment outcomes in Debre Berhan referral hospital
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