TRENDS AND OUTCOMES OF BRONCHIECTASIS–RELATED HOSPITALIZATION IN THE UNITED STATES FROM 2015 TO 2018

Abstract

TOPIC: Obstructive Lung Diseases TYPE: Original Investigations PURPOSE: The burden of bronchiectasis on health system is not well known due to lack of data on prevalence and trends of the disease. This study was aimed to determine the age- and gender-adjusted national trends in bronchiectasis-related hospitalizations in the United States using the largest nationally representative database. METHODS: We performed a cross-sectional study of the National Inpatient Sample database for all adult patients (≥ 18 years old) with bronchiectasis as the principal diagnosis from October 1, 2015 to December 31, 2018. We analyzed the age- and gender-adjusted longitudinal trends in hospital admissions, in-hospital mortality, hospital charges, and hospital length of stay. RESULTS: Between 2015 to 2018, the number of bronchiectasis-related hospitalizations and in-hospital mortality has remained stable. The proportion of diabetes patients among bronchiectasis has significantly decreased from 2015 to 2018, from 20.93% to 10.91% (p<0.001). Moreover, the number of patients with bronchiectasis managed at teaching tertiary hospitals has significant increased from 73.8% to 78.3% (p=0.008). There was no significant increase in hospital charges and hospital length of stay. CONCLUSIONS: Analyses of temporal changes in bronchiectasis showed stable hospitalizations and in-hospital mortality among patients with bronchiectasis, with a decrease in proportion of co-morbid condition of diabetes. CLINICAL IMPLICATIONS: Further studies should be conducted exploring the relationship of diabetes and bronchiectasis to aid understanding of the disease process and provide optimal care. DISCLOSURES: No relevant relationships by Jeeyune Bahk, source=Web Response No relevant relationships by Jennifer Fung, source=Web Response No relevant relationships by Kam Sing Ho, source=Web Response