Abstract

Acute myocardial infarction (AMI) poses a serious disease burden in China, but studies on small-area characteristics of AMI incidence are lacking. We therefore examined temporal trends and geographic variations in AMI incidence at the township level in Beijing. In this cross-sectional analysis, 259,830 AMI events during 2007–2018 from the Beijing Cardiovascular Disease Surveillance System were included. We estimated AMI incidence for 307 consistent townships during consecutive 3-year periods with a Bayesian spatial model. From 2007 to 2018, the median AMI incidence in townships increased from 216.3 to 231.6 per 100,000, with a greater relative increase in young and middle-aged males (35–49 years: 54.2%; 50–64 years: 33.2%). The most pronounced increases in the relative inequalities was observed among young residents (2.1 to 2.8 for males and 2.8 to 3.4 for females). Townships with high rates and larger relative increases were primarily located in Beijing’s northeastern and southwestern peri-urban areas. However, large increases among young and middle-aged males were observed throughout peri-urban areas. AMI incidence and their changes over time varied substantially at the township level in Beijing, especially among young adults. Targeted mitigation strategies are required for high-risk populations and areas to reduce health disparities across Beijing.

Highlights

  • Ischemic heart disease is a leading cause of death worldwide and in China [1,2]

  • The median age- and sex-standardized Acute myocardial infarction (AMI) incidence rate increased by 7.1% from 216.3 per 100,000 population in 2007–2009 to 231.6 per 100,000 population in 2016–2018

  • We found increases in AMI incidence rates of 50% or greater for young and middle-aged males aged 35–64 years in almost all peri-urban areas

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Summary

Introduction

Ischemic heart disease is a leading cause of death worldwide and in China [1,2]. Acute myocardial infarction (AMI) is a serious manifestation of ischemic heart disease and is often fatal. Limited data on temporal trends for AMI incidence are available for low- and middle-income countries. Beijing is one of the most populous global cities In recent decades, this city has experienced rapid economic and population growth and subsequent social and environmental changes, such as air pollution, rapid urbanization and lifestyle change, that have been correlated to cardiovascular risk in other populations [5,6]. The recent temporal trends in AMI incidence in Beijing, and their magnitude, remain unclear

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