Trend of HIV-TB co-morbidity?in north-west region of Uttarakhand

Abstract

Tuberculosis (TB) is the commonest opportunistic infection and the number one cause of death in HIV patients in developing countries. HIV co-infection is the most powerful known risk factor for progression of M. tuberculosis infection to active disease, increasing the risk of latent TB reactivation. The study was carried out to study the trend of Tuberculosis in HIV seropositive patients and determine HIV-TB co-morbidity in Dehradun, Uttarakhand. A retrospective study of standardized patient records was conducted from December 2017 to November 2018 of all HIV sero-positive patients registered to ART PLUS Centre Govt. Doon Hospital Dehradun. TB suspected patients were referred to RNTCP. Data was taken and analyzed by Microsoft Excel. Among total of 18319 HIV positive patients attending ART centre (ART and Pre- ART enrolled) during the study period, 585 patients were suspected of TB and were referred from ART to RNTCP. Total 128 (21.9%) patients were diagnosed with TB, of which 71(55.46%) patients were diagnosed for pulmonary TB and 57(44.5%) were Extra-Pulmonary TB. In our study Male predominance was seen and most of the cases were of age group 19-40 years, mostly belonging to rural areas. Keywords: HIV/AIDS, Tuberculosis, Co-infection.