Abstract
BackgroundAmong different common types of cancer, gastric cancer (GC) is a worldwide health priority in both developing and developed countries. The aim of this study was to map the distribution of incident cases of GC in Iran to provide a geographical presentation of the incidence of the disease.MethodsThis study used the Iranian National Cancer Registry (INCR) data from 2004 to 2014. We calculated the crude and age-standardized incidence rates of GC for each province and also defined the frequency distribution of different types and locations of GC by the provinces.ResultsAccording to the results of the present study, the patients were predominantly male 49,907 (70.0%) and the most prevalent type of tumour was A1 (almost 96.4%) and C3 (2.0%). Also, a significant difference was observed between males and females in the distribution of the types of tumour (P < 0.001). In addition, a comparison of the distribution of the types of GC in Iran suggested that a significant difference exists between the provinces (P < 0.001). A significant difference was observed when the distribution of the location of GC tumors was compared between males and females and provinces (P < 0.001). Accordingly, pylori and cardia are the most common location of GC cancer among the study population (28.1% and 31.3% respectively).ConclusionsThe results of the current study suggested a higher rate of GC incidence in Iran when compared to the global figure in both females and males. Our study also revealed significant disparities between provinces with regard to the distribution of types, and location of GC. This may suggest involving different factors in GC in different parts of Iran. Further studies are needed to better understand the epidemiology and etiology of the disease in Iran.
Highlights
Among different common types of cancer, gastric cancer (GC) is a worldwide health priority in both developing and developed countries
The aim of this study was to map the distribution of incident cases of GC in Iran to provide a geographical presentation of the incidence and pathology of the disease
The 10-year incidence rates of stomach cancer by age and sex are presented in Table 1 and Additional file 1, 2: Figs
Summary
Among different common types of cancer, gastric cancer (GC) is a worldwide health priority in both developing and developed countries. As a result GC is a worldwide health priority in both developing and Moradian et al BMC Gastroenterology (2022) 22:4 transitions, the number of incident cases of gastric cancer is rising constantly [4]. This is why, currently, the incidence of gastric cancer is the first cause of death due to cancer in Iran [5]. With regard to the pathology and clinical aspects of GC, the anatomic appearance of cancer (cardia and non-cardia) and histological type of the disease (enteric and non-enteric) are two important characteristics of GC These features may come with different etiology, symptoms, and even prognosis. Dietary habits, physical inactivity, smoking, alcohol use, obesity, and family history of the disease, factors that are globally distributed with high discrepancy [11]
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