Abstract
Hepatitis B is one of the transfusion transmissible infections. The prevalence of this infection varies across the different geographies. Noting the trend in seroprevalence is useful to assist the preventive strategies. The aim of this study was to determine the trend of seroprevalence of hepatitis B in costal Karnataka over a three-year period. The study was conducted at the blood bank of a tertiary care hospital serving predominantly the people of coastal Karnataka. A retrospective analysis of blood donors over a period of three years was done to assess the seroprevalence and the trend of hepatitis B infection. ELISA was used to detect the hepatitis B surface antigen in the donors as a marker of infection. A total of 30,428 blood donors were studied. 189 (0.62%) were positive, which comes under the "low prevalence ( < 2%) zone" per World Health Organization (WHO) guidelines. A decreasing trend over three years was seen. Replacement donors and male blood donors showed higher seropositivity compared to voluntary donors and female donors. Chi-square test was used to calculate the significance of difference between the groups. Coastal Karnataka has a low prevalence of hepatitis B in blood donors with a decreasing trend over the last three-year period.
Highlights
Hepatitis B is a major public health problem worldwide
In the present retrospective study, we evaluated the seroprevalence of hepatitis B virus among blood donors in coastal Karnataka
The observed seroprevalence of hepatitis B virus (HBV) was higher in replacement donors than in voluntary donors (0.65% vs. 0.42%, respectively, Table 2)
Summary
Hepatitis B is a major public health problem worldwide. Approximately 30% of the world’s population or about 2 billion persons have serological evidence of either current or past infection with hepatitis B virus [1]. The study aimed to determine the trend in hepatitis B infection and to compare the prevalence with that of other areas in India. The results of these prevalence studies should help in the creation of long-term strategies to improve public health and to prevent spreading of the disease in the local population. A retrospective analysis of blood donors over a period of three years was done to assess the seroprevalence and the trend of hepatitis B infection. Conclusion: Coastal Karnataka has a low prevalence of hepatitis B in blood donors with a decreasing trend over the last three-year period
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
