Abstract

 CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
 The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
 This review assesses tremelimumab (Imjudo), 20 mg/mL, concentrate IV infusion in combination with durvalumab (Imfinzi), 50 mg/mL, concentrate for IV infusion.
 Indication: Proposed: Imjudo (tremelimumab for injection) in combination with durvalumab is indicated for the first-line treatment of adult patients with unresectable hepatocellular carcinoma who require systemic therapy.
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