Abstract
A 71-year-old-woman mentioned a selective digestive intolerance to mushrooms. The syndrome could be reproduced by ingestion of trehalose. The small variations of blood glucose during a trehalose tolerance test suggested very poor, if any, hydrolysis of trehalose. Comparative tests with glucose, sucrose, and maltose indicated normal absorption of these sugars. Since no enzymatic assay of the intestinal mucosa could be performed, the results observed were compared with those of 16 control subjects. It is concluded that malabsorption of trehalose owing to a selective deficiency in intestinal trehalase could be the cause of this intolerance to mushrooms.
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