Abstract

various molecules present in the type I IFN signaling pathway. The oral administration of Epimedium Koreanum Nakai exhibited both preventive and therapeutic effects on BALB/c mice against lethal doses of highly pathogenic influenza A subtypes containing H1N1, H5N2, H7N3 and H9N2. Conclusion: Our results clearly indicated that Epimedium Koreanum Nakai contains components that play roles as immunomodulators and may be potential candidates for new antiviral drugs. Contact: Won-Kyung Cho, wkcho@kiom.re.kr

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