Treatment status of parenteral nutrition-associated cholestasis in preterm infants

Abstract

Parenteral nutrition (PN) is one of the important measures to cure premature babies and critically ill infants. In recent years, with the improvement of rescue techniques in the perinatal period, a growing number of preterm infants alive, very low birth weight and low birth weight infants gradually become an important part of the neonatal disease. The gastrointestinal development of these premature babies are not mature or combined with other diseases, in a long period of time after birth need partial or complete PN support. Due to the use of PN, provides the children with survival and greatly reduce the case fatality rate, but the cause of parenteral nutrition associated cholestasis would become one of the main complications of premature infants, seriously affect the patient′s quality of life. In this paper, the treatment of premature parenteral nutrition associated cholestasis status is summarized. Key words: Parenteral nutrition; Cholestasis; Treatment; Premature infant