Abstract

Objectives This study had the goal of evaluating the role of treatment satisfaction among diabetic patients in the context of health-related quality of life (QoL) and medication adherence. Methods This study, which utilized a cross-sectional design, was conducted at the Primary Healthcare Unit in the Ministry of Health in Ramallah between Feb. and May 2019. Medication adherence was evaluated with the 4-item Morisky Green-Levine (MGL) questionnaire, treatment satisfaction using the Treatment Satisfaction Questionnaire for Medication version 1.4 (TSQM 1.4), and health-related quality of life with the European Quality of Life scale (EQ-5D-3L). Results Study participants consisted of 380 diabetic patients, of which 220 (57.9%) had high adherence to their medications and 160 (42.1%) had low adherence. Based on the classification of patient responses among the EQ-5D domains, pain/discomfort was the most influenced dimension, with 173 patients (36.1%) reporting problems, (36.1%). Also prominent were anxiety and depression (128 patients, 33.7%) and Mobility (115 patients, 30.3%). A significant relation was observed between QoL and treatment satisfaction (73.8 vs. 69.8; P = 0.016). Treatment satisfaction also had a significant association with the anxiety domain (39.4 vs. 28.7; P = 0.031). Conclusion Participants expressed moderate satisfaction with their treatments; more satisfied patients showed greater medication adherence and had better QoL. Anxiety has been shown to be associated with reduced medication adherence and lower QoL.

Highlights

  • The chronic progressive disease diabetes mellitus (DM) is associated with elevated blood glucose level caused by impaired insulin production, impaired insulin function, or both [1]

  • The duration of the first diabetes diagnosis for approximately 30% of patients was at least 10 years

  • Hyperlipidemia was a major complication of T2DM in (14.5%) of patients, while CVD affected (2.4%) of patients

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Summary

Introduction

The chronic progressive disease diabetes mellitus (DM) is associated with elevated blood glucose level (hyperglycemia) caused by impaired insulin production, impaired insulin function, or both [1]. The burden of diabetes is increasing due to the universal increase in the prevalence of obesity and unhealthy lifestyles [3]. The worldwide prevalence of diabetes was about 8% in 2011 and is predicted to rise to 10% by 2030, making DM a major cause of death globally [4]. The prevalence of DM in Palestine has increased significantly [5], leading to increased risk of complications, rates of morbidity and mortality, and spending on health care. The degree to which a patient implements lifestyle changes follows a diet or takes medication in keeping with the instructions of their health care provider is referred to as adherence [8]

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