Treatment Patterns and Outcomes in Pregnancy-Associated Adenocarcinoma of the Cervix

Abstract

Abstract Objective: Cervical cancer occurs in ∼1/2200 pregnancies. Limited data exist for optimal management of cervical adenocarcinomas, which have seen a disproportionate rise in incidence. The purpose of this study was to evaluate treatment patterns and outcomes in pregnancy-associated cervical adenocarcinoma (AC) or adenosquamous carcinoma (AS). Design: This was a retrospective observational study. Materials and Methods: Patients at a single institution diagnosed between 1990 and 2009 with cervical AC or AS during pregnancy, and within 6 weeks postpartum, were reviewed. Charts were reviewed for demographic, pathologic treatment, and outcome data. Results: Thirteen patients were identified with stage IA (2), IB (10), and IIIB (1) disease. Treatment for invasive cancer diagnosed during pregnancy included abortion followed by chemoradiation, cold knife cone (CKC) followed by cesarean radical hysterectomy, radical hysterectomy, and antenatal loop electrosurgical excision procedure (LEEP) with cesarean del...