Treatment Outcomes of Facial Rejuvenation With a Novel Hyaluronic Acid Filler in Asian Women

Abstract

We conducted this study to assess the short-term treatment outcomes and safety of facial rejuvenation with the YVOIRE volume plus (LG Chem Ltd., Seoul) in Asian women. In this multicenter, retrospective study, we evaluated a total of 291 women (n = 291) who received a facial rejuvenation with the YVOIRE volume plus. We monitored time-dependent changes in the mean Global Aesthetic Improvement Scale (GAIS) scores at 3, 6, 9, and 12 months. In addition, we estimated the duration of efficacy based on the Kaplan-Meier survival analysis. Furthermore, we analyzed incidences of postoperative complications. Our clinical series of the patients achieved mean GAIS scores of 3.44 ± 0.69 points. There were no significant time-dependent changes in the mean GAIS scores ( P > .05). Moreover, the duration of efficacy was estimated at 242.71 ± 17.85 days (95% confidence interval: 228.59-263.44). A total of 37 cases (12.7%) of postoperative complications occurred, all of them were of mild severity. In conclusion, our surgical technique, combined with YVOIRE volume plus, is of significance in that it attempted to address both dynamic and static aspects of the facial rejuvenation. But this deserves further studies using 3-dimensional imaging modalities.