Treatment Outcome of Pulmonary and Extra Pulmonary Tuberculosis Patients Registered at DOTS Centre in a Tertiary Care Hospital, Mysuru, Karnataka, India

Abstract

Aim: To compare the personal variables, clinical characteristics and treatment outcome of Pulmonary and Extra Pulmonary Tuberculosis (EPTB) patients.
 Settings and Design: A Retrospective observational study was conducted in Directly Observed Treatment Short term (DOTS) centre of teaching hospital, Mysuru, Karnataka state in India from December 2019 to December 2020.
 Methods and Materials: All newly diagnosed patients were registered and followed up during their course of treatment to assess treatment outcome. Data is collected by using personal variable proforma and clinical characteristic form.
 Results: Among 197 tuberculosis (TB) patients’ 120(60.91%) were suffering with EPTB and the remaining 77(39.08%) have the PTB. Majority 101(51.26%) patients were diagnosed by microbiological confirmation and remaining 96(48.73%) were clinically diagnosed. Even though majority 140 (71.06%) completed the treatment only 10(5.07%) were cured. About 16(8.12%) TB patients have treatment failure and were lost to follow up. The treatment success rate was (0.5%). Confirming the presence of TB by microbiologically and clinically is having influence in diagnosis of EPTB, as well as consumption of alcohol was having statistical significance inferring these clinical characteristics having influence in developing EPTB. Residence of the patient is a risk factor for the treatment outcome as per calculated odds ratio
 Conclusion: The mean treatment success rate of PTB patients was 80.59% and in EPTB was 73.33%. The treatment success rate was not significantly affected by gender, age and type of TB. .