Abstract
Intratympanic infusion (IT) injection of corticosteroids is increasingly used after treatment failure with conventional therapy. In this study, we investigate the effectiveness of IT administration. We included 30 patients presenting with SSHL, who were divided into two groups. Group A consisted of 18 patients who were administered IV therapy with vasodilators and corticosteroids for 10 days. If this therapy failed, they were injected IT methylprednisolone. Group B consisted of 12 patients who were immediately administered IT corticosteroids .We injected 0.4 mL of 125 mg/mL methylprednisolone, twice on the first week and once a week for the following 4 weeks. An audiogram was performed before each injection, 1 and 3 months after the last session. Group A showed an improvement of 12 dB in mean, and group B showed an improvement of 9.5 dB. The IT steroid administration appears to be a reasonable alternative, especially in patients who do not respond to or cannot receive systemic steroids.
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