Abstract
To the Editor:— Recent articles inThe Journalon the use of medicinal agents to treat chronic typhoid and paratyphoid carriers have been interesting to health authorities. Following the optimistic reports of Saphir and Howell (May 18, 1940, p. 1988) and of Enright (Jan. 18, 1941, p. 220), the Division of Communicable Disease of the New York State Health Department studied the efficacy of soluble iodophthalein in several carriers. The results were unsuccessful, similar to those more recently reported by Saphir, Baer and Plotke (March 21, 1942, p. 964) and by Cutting and Robson (April 25, 1942, p. 1447). With the cooperation and active help of Dr. Kenneth Keill and Dr. W. M. Pamphilon of the Willard State Hospital, Willard, N. Y., six known chronic typhoid carriers were treated at that institution. The results are summarized in the accompanying table. In each of the instances it was known that the
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