Abstract

ABSTRACT To the Editor:— There appeared in a recent issue of The Journal (April 25, p. 1447) an article by Drs. Windsor C. Cutting and G. Bernard Robson entitled Treatment of Typhoid Carriers. According to this paper, treatment of 5 typhoid carriers with soluble iodophthalein failed to cure the carrier state.Although it is realized that the authors did not have knowledge of our recently published study (ibid., March 21, p. 964), it appears that the reader of The Journal may be wrongly impressed with the value of such treatment. It is for this reason that we desire to make the following statements:The iodophthalein treatment is not an all out cure of all typhoid carriers. Only a definite, well defined group of carriers will respond to treatment. These are carriers who present typhoid bacilli in their bile, as obtained by duodenal drainage, and a well functioning gallbladder, as determined

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