Abstract
A pregnant woman who had oropharyngeal tularemia underwent treatment with azithromycin and lymph node resection and recovered without obstetrical complication or infection in the child. Azithromycin represents a first-line treatment option for tularemia during pregnancy in regions where the infecting strains of Francisella tularensis have no natural resistance to macrolides.
Highlights
Tularemia is a bacterial zoonotic disease caused by a gram-negative coccobacillus, Francisella tularensis; the most virulent subspecies, tularensis (type A), is found in North America, but subspecies holarctica (type B) occurs throughout the Northern Hemisphere [1,2,3,4]
Tularemia is a bacterial zoonotic disease caused by a gram-negative coccobacillus, Francisella tularensis; the most virulent subspecies, tularensis, is found in North America, but subspecies holarctica occurs throughout the Northern Hemisphere [1,2,3,4]
Clinical symptoms of tularemia are primarily related to the portal of entry of bacteria, the F. tularensis strain virulence, and the immune status of the patient
Summary
Tularemia is a bacterial zoonotic disease caused by a gram-negative coccobacillus, Francisella tularensis; the most virulent subspecies, tularensis (type A), is found in North America, but subspecies holarctica (type B) occurs throughout the Northern Hemisphere [1,2,3,4]. The Case In late February 2006, a 27-year-old pregnant woman, at 6 weeks’ gestation, was referred to Grenoble University Hospital, Grenoble, France, for investigation of persistent left cervical lymphadenopathy with fever. Examination of the removed lymph node samples confirmed the presence of nonspecific lymphadenitis.
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