Abstract
I. Introduction In a previous paper 1 we reported the successful treatment of 2 eyes with traumatic total hyphema and secondary glaucoma by irrigation with fibrinolysin. The present paper reports data on 8 eyes treated by us and on 56 eyes submitted to us by other ophthalmologists. Fibrinolysin (Thrombolysin)* is a proteolytic enzyme prepared commercially by exposing high concentrations of purified profibrinolysin from human plasma to an activator substance, purified streptokinase. Fibrinolysin has a lytic effect on the fibrin clot, which is dissolved and can be irrigated from the anterior chamber. We also are reporting experimental work with fibrinolysin used in rabbit eyes. II. Experimental Studies Purpose .—Experiments were set up to evaluate the effect of various concentrations of fibrinolysin on ocular tissues when used in the rabbit anterior chamber. The effect of fibrinolysin on experimentally produced hyphema in the rabbit eye was also investigated. Method of Study .—Albino rabbits
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
