Treatment of Tendon, Muscle and Ligament Injuries and Degenerative Joint Disorders with Homologous Platelet Rich Plasma Injection

Altuntas Z,Altuntas M,Savaci N

doi:10.4172/2472-1905.100041

Abstract

Background: Recently, PRP are being used to treat acute and chronic injuries in an attempt to jump start healing due to being too much growth factor source. However, the homologous platelet rich plasma has been investigated in several studies to treat chronic wounds. In this study, we used H-PRP injection for tendon, muscle and ligament injuries and degenerative joint disorders. Our objective was to use homologous PRP for the treatment of tendon, muscle and ligament injuries and degenerative joint disorders and investigate the effects of it. Methods: We applied 164 injection of homolog PRP to 109 patients. We repeated the injection in 17 patients. The 139 injection were made intra-articulacy patients and 25 injections were applied to the soft tissue. We followed all of the patients for one year. Results: No severe adverse events or complications related to the injections were observed during the treatment or follow-up period. All of the patients were very satisfied with the treatment and had reported pain relief and increase of their life standards subjectively. Second session was performed to the seventeen patients after six months. Sixteen of them had resumed knee pain and one of them had temporomandibular joint pain. However, we also observed no side effects with patient satisfaction. Conclusion: This study showed Homologous PRP could be safely used without any adverse effects to treat the patients of tendon, muscle and ligament injuries and degenerative joint disorders with high patient satisfaction.

Highlights

The use of autologous platelet rich plasma is increasing in an effort to facilitate healing in a variety of clinical disorders
The better understanding of the biology of wound healing suggests that the platelets play a main role on roles in fundamental processes, including inflammation, angiogenesis, cell migration, and metabolism, in pathological conditions
The patients with a history of chronic pain with no benefit from previous analgesic treatments or physiotherapy and the presence of grade 3-4 osteoarthritis according to the Ahlbach’s classification system based on AP weight bearing and lateral views of knees were included in this study. 7 of them had hypertension and 3 had diabetes mellitus. 6 patients were smoker

Summary

Introduction

The use of autologous platelet rich plasma is increasing in an effort to facilitate healing in a variety of clinical disorders. The homologous platelet rich plasma has been investigated in several studies to treat chronic wounds. We used H-PRP injection for tendon, muscle and ligament injuries and degenerative joint disorders. Our objective was to use homologous PRP for the treatment of tendon, muscle and ligament injuries and degenerative joint disorders and investigate the effects of it. Methods: We applied 164 injection of homolog PRP to 109 patients. Conclusion: This study showed Homologous PRP could be safely used without any adverse effects to treat the patients of tendon, muscle and ligament injuries and degenerative joint disorders with high patient satisfaction

Objectives

Results

Conclusion