Treatment of tardive dystonia due to risperidone use with single-dose botulinum toxin

Abstract

Late-onset dystonia occurs after long-term antipsychotic treatment or after discontinuation of treatment. Being young, male gender, mental retardation, and mood disorder are risk factors. By considering the dystonic complaints and psychotic symptoms of the patient who had a diagnosis of schizoaffective disorder and had risperidone 8 mg/day tablet use for 3 months, it was planned to continue treatment with clozapine. When the dystonic complaints did not improve, botulinum toxin was applied and recovery was achieved. In most cases, botulinum toxin can provide a dramatic improvement in the treatment of tardive dystonia, which is very difficult to treat and causes significant loss of functionality and poor quality of life. For this reason, botulinum toxin application should come to mind in the treatment of tardive dystonia.