Treatment of Still's disease with isoniazid.

Abstract

UNDER the title, Rimifon and Still's Disease, we previously published a preliminary report on a case of Still's disease, or atrophic rheumatoid arthritis. Furthermore, under the title Isonicotinic Acid Derivatives in Different Abnormal Conditions, we have reported to the Greek Pediatric Society on Feb. 24, 1953, a summary of the therapeutic effects of isoniazid in the same case to the above date. REPORT OF A CASE M. K., a girl aged 6 years, was admitted to the hospital on July 13, 1952. She was the second child of healthy parents and was born without complications after a normal pregnancy. One year prior to admission she underwent a tonsillectomy. At the time of admission she had a nine-month history of moderate fever and painful, gradually swelling joints, fusiform in shape, with stiffness and limitation and loss of movement. She was cachectic and melancholy. Physical examination on admission revealed pallor, sunken eyes,