Abstract
IntroductionStasis purpura is a common finding in clinical practice and is related to vascular alterations.Case presentationFour randomly-selected, Caucasian patients (a 45-year-old woman, a 26-year-old man, a 51-year-old man and a 56-year-old woman) were treated with aminaphtone for approximately one year. For all patients, the brown patches - a sign of stasis purpura - disappeared without the appearance of new lesions within this period.ConclusionAminaphtone is a novel proposal in the treatment of stasis purpura when capillary fragility is identified.
Highlights
Stasis purpura is a common finding in clinical practice and is related to vascular alterations.Case presentation: Four randomly-selected, Caucasian patients (a 45-year-old woman, a 26-year-old man, a 51-year-old man and a 56-year-old woman) were treated with aminaphtone for approximately one year
Dermal melanocytes containing melanin and incontinence of melanin pigment were observed, which suggests that melanin pigment from the epidermis may contribute to cutaneous pigmentation in stasis dermatitis [4]
There is a scarcity of therapies to treat stasis dermatitis recorded in the literature; the use of substances that control capillary fragility may be useful to control bleeding [5]
Summary
Chronic venous disease (CVD) is common with manifestations that include varicose veins, skin changes such as dermatitis, hyperpigmentation, lipodermatosclerosis, and chronic leg ulcers [1]. Case 1 A 45-year-old Caucasian woman presented with brown patches on the lower third of her leg, which had been present for three years prior to our interview Case 2 A 26-year-old Caucasian man presented with a history of brown patches on both legs that had started two years previously with the appearance of reddish spots. The presence of brown patches de Godoy Journal of Medical Case Reports 2010, 4:295 http://www.jmedicalcasereports.com/content/4/1/295 together with reddish spots was confirmed, predominantly on the distal third of his legs including his ankle region. He did not suffer from varicose veins or telangiectasias. No new lesions have appeared over the last two years
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