Abstract
AbstractBackground: Human bone marrow has shown promise as a minimally invasive approach in treating a variety of musculoskeletal conditions due to the presence of stem cells, platelets, and growth factors in solution. This study examines the clinical effect of whole bone marrow (WBM) and bone marrow concentrate (BMC) injections in patients who were diagnosed with rotator cuff tears or shoulder osteoarthritis. Methods: Forty-seven patients and fifty shoulders with rotator cuff tears or shoulder osteoarthritis underwent one or two BMC or WBM treatments. These patients were grouped based on number of treatments and pathology for analysis. The patients who were injected twice received them approximately 22.33 days apart. Outcomes of resting pain, active pain, upper extremity functionality scale and overall improvement percentage were compared to baseline and between groups. Results: Patients who received either one and two treatments reported significant improvements in resting pain, active pain, and functio...
Highlights
Chronic shoulder pain is the third most common cause of musculoskeletal pain affecting approximately 4.5 million patients and costing in excess of $7 billion per year in the United States (Mather et al, 2013; Oh, Wolf, Hall, Levy, & Marx, 2007; Pope, Croft, Pritchard, & Silman, 1997)
The purpose of our study was to report the clinical outcomes of patients diagnosed with shoulder osteoarthritis or rotator cuff tears when injected with bone marrow derived therapies
Common shoulder pathologies include anterior shoulder instability, biceps tendinitis, lesions to the acromioclavicular joint, and proximal humeral fractures; the most common pathologies resulting in chronic shoulder pain are rotator cuff tears (RCT) and glenohumeral osteoarthritis (OA) (Herin, Vézina, Thaon, Soulat, & Paris, 2012)
Summary
Chronic shoulder pain is the third most common cause of musculoskeletal pain affecting approximately 4.5 million patients and costing in excess of $7 billion per year in the United States (Mather et al, 2013; Oh, Wolf, Hall, Levy, & Marx, 2007; Pope, Croft, Pritchard, & Silman, 1997). This study examines the clinical effect of whole bone marrow (WBM) and bone marrow concentrate (BMC) injections in patients who were diagnosed with rotator cuff tears or shoulder osteoarthritis. Methods: Forty-seven patients and fifty shoulders with rotator cuff tears or shoulder osteoarthritis underwent one or two BMC or WBM treatments. These patients were grouped based on number of treatments and pathology for analysis. Results: Patients who received either one and two treatments reported significant improvements in resting pain, active pain, and functionality score when compared to baseline. These groups experienced a 42.25% and 50.17% overall improvement respectively. Conclusions: Our study demonstrated that patients diagnosed with shoulder osteoarthritis or rotator cuff tears experienced
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