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Abstract
To the Editor: Shiitake (Lentinus edodes) dermatitis, also called toxicoderma, is a characteristic acute skin reaction that occurs after eating raw or half-cooked shiitake. Shiitake are semi-toxic mushrooms that contain the heat-labile toxin lentinan.1-3 Shiitake dermatitis mainly occurs in Japan, although these mushrooms are also cultivated worldwide. Thus shiitake dermatitis has become more common in recent years in Europe and the United States. Multiple cases have been published since the first report by Nakamura1 in 1977, but to date there is no effective therapy.
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