Abstract
ObjectiveTo explore the new treatment strategies for radiation proctitis, which is the most common complication of pelvic tumor malignancies. MethodsFour cases of patients with severe radiation proctitis were treated with high-dosage vitamin C (VC, 12–24 g/d, iv) combined with cyclooxygenase-2 (cyclooxygenase-2, COX-2) inhibitors. ResultsFor these four cases, the diarrhea, hematochezia, tenesmus, pain, and other symptoms were significantly improved. The edema of the rectal wall is also significantly improved in the imaging review. ConclusionThe high-dosage VC combined with the treatment of severe radiation proctitis is safe and effective.
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