Abstract

This article reports the resolution of a case of severe oral mucositis and the treatment protocol that promoted complete remission of the lesions. A male 13-year-old patient with chondroblastic osteosarcoma in the left distal thigh and acute lymphoblastic leukemia undergoing cancer treatment with methotrexate presented with severe oral mucositis. The treatment protocol included the use of 10ml of a mucositis mouthwash and low-level laser therapy. The lesions remitted after five days of gargling with the mucositis mouthwash and two sessions of low-level laser therapy on the lesions. The use of a treatment protocol consisting of a mucositis solution associated with low-level laser therapy effectively resolved a case of severe chemotherapy-induced oral mucositis. The monitoring and treatment of oral mucositis lesions in children and adolescents undergoing chemotherapy are necessary to prevent the patient from suffering from induced comorbidities.

Highlights

  • Chemotherapy-induced mucositis is one of the most important undesirable side effects of cancer treatment, promoting the worst cases of morbidity, increasing length of hospital stay, and frequently reducing the odds of controlling the tumor and the patient’s life expectancy[1].Ulcers caused by oral mucositis can be an important source of systemic infection, especially in immunosuppressed patients[2,3]

  • This study aimed to report the resolution of a case of severe oral mucositis and demonstrate the intervention protocol used by the pediatric sector of the Hospital Napoleão Laureano (João Pessoa, PB) for treating these cases

  • Commonly present in pediatric cancer patients[1,7,8], are associated with the type, dose, and administration frequency of anticancer agents[9,10], and with factors such as neutropenia, which in general occurs about 15 days after anticancer drug admistration[1]; this length of time coincides with the presence of oral mucositis in children and adolescents[9]

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Summary

Introduction

Chemotherapy-induced mucositis is one of the most important undesirable side effects of cancer treatment, promoting the worst cases of morbidity, increasing length of hospital stay, and frequently reducing the odds of controlling the tumor and the patient’s life expectancy[1].Ulcers caused by oral mucositis can be an important source of systemic infection, especially in immunosuppressed patients[2,3]. Chemotherapy-induced mucositis is one of the most important undesirable side effects of cancer treatment, promoting the worst cases of morbidity, increasing length of hospital stay, and frequently reducing the odds of controlling the tumor and the patient’s life expectancy[1]. Oral mucositis induces pediatric patients to reduce food intake, which affects their nutritional status and makes them less responsive to treatment[4,5]. Sonis et al.[5] reported that 78% of chemotherapy patients presented with mucositis at some point during treatment. This study aimed to report the resolution of a case of severe oral mucositis and demonstrate the intervention protocol used by the pediatric sector of the Hospital Napoleão Laureano (João Pessoa, PB) for treating these cases.

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