Treatment of scoliosis in osteogenesis imperfecta: Experience at a single institution

Abstract

Background: Spinal deformities are frequently seen in osteogenesis imperfecta (OI). We investigated contemporary spinal fusion techniques including pedicle screw fixation with or without cement augmentation in OI patients with scoliosis. Materials and Methods: OI patients with posterior-only scoliosis surgery were reviewed retrospectively (2005–2017). Preoperative and postoperative clinical status was compared. The radiographic review included pelvic obliquity, major curve magnitude, coronal balance, apical vertebral translation (AVT), lowest instrumented vertebrae (LIV) tilt angle, proximal and distal junctional angle, T1–S1 distance, and T1-pelvic angle. Results: Sixteen patients were included in the study. The mean age at surgery was 14 years (range, 6–19). The average follow-up period was 80 ± 40 months (range, 24–148). Mean preoperative curve magnitude of 76° ± 19° was significantly larger than the initial (31° ± 16°) and final (32° ± 17°) postoperative curve magnitudes (58% correction; P