Abstract

IntroductionNumerous studies across different health systems have documented that many patients with rheumatoid arthritis (RA) do not receive disease-modifying anti-rheumatic drugs (DMARDs). Relatively little is known about correlates of DMARD use and whether there are socioeconomic and demographic disparities. We examined DMARD use during 2001 to 2006 in the Medicare Current Beneficiary Survey (MCBS), a longitudinal US survey of randomly selected Medicare beneficiaries.MethodsParticipants in MCBS with RA were included in the analyses, and DMARD use was based on an in-home assessment of all medications. Variables included as potential correlates of DMARD use in weighted regression models included race/ethnicity, insurance, income, education, rheumatology visit, region, age, gender, comorbidity index, and calendar year.ResultsThe cohort consisted of 509 MCBS participants with a diagnosis code for RA. Their median age was 70 years, 72% were female, and 24% saw a rheumatologist. Rates of DMARD use ranged from 37% among those <75 years of age to 25% of those age 75 to 84 and 4% of those age 85 and older. The multivariable adjusted predictors of DMARD use include: visit with a rheumatologist in the prior year (odds ratio, OR, 7.74, 95% CI, 5.37, 11.1) and older patient age (compared with <75 years, ages 75 to 84, OR 0.58, 95% CI 0.37, 0.92, and 85 and over, OR 0.09, 95% CI 0.02, 0.31). In those without a rheumatology visit, lower income and older age were associated with a significantly reduced probability of DMARD use; no association of DMARD use with income or age was observed for subjects seen by rheumatologists. Race and ethnicity were not significantly associated with receipt of DMARDs.ConclusionsAmong individuals not seeing rheumatologists, lower income and older age were associated with a reduced probability of DMARD use.

Highlights

  • Numerous studies across different health systems have documented that many patients with rheumatoid arthritis (RA) do not receive disease-modifying anti-rheumatic drugs (DMARDs)

  • Similar to other community-based studies, we found suboptimal DMARD use among Medicare Current Beneficiary Survey (MCBS) beneficiaries diagnosed with RA; approximately one-third of follow-up time in this study cohort demonstrated any Number of patients Any DMARDS Non-biologic DMARD

  • Older age and lower income were associated with a reduced likelihood of DMARD use

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Summary

Introduction

Numerous studies across different health systems have documented that many patients with rheumatoid arthritis (RA) do not receive disease-modifying anti-rheumatic drugs (DMARDs). Rheumatic disease experts and their professional societies widely embrace the importance of early and sustained use of disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis (RA) [1,2] Despite this recommendation, several population-based and community-based studies demonstrate under-use of these agents. All studies that have examined the inclusion of a rheumatologist in a patient’s care have found this factor to be the strongest predictor of DMARD use, with a 2- to 7-fold increase in prescribing among patients seeing a rheumatologist [4,5,7,8]. These findings are consistent across various countries

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