Abstract
To the Editor: Chronic urticaria is a physically and emotionally debilitating condition that often fails to respond adequately to antihistamines. Systemic therapy with glucocorticoids, sulfasalazine, colchicine, intravenous immunoglobulin, dapsone, or other immunosuppressants including cyclosporine, cyclophosphamide, and methotrexate are used in many patients with the associated risks of renal and hepatic toxicity and anemia. Unfortunately, some patients have disease recalcitrant to these treatments.
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