Abstract
in 13 cases (68 4%). 15 had a second transplant during the study period. Overall graft survival at 2 years was 26.3% after first allograt~ and 78.9% after re-kT The mean age at time of tJrst LT was 48 years. 733% of patients were male MELD score at time of second transplant was higher when compared with MELD score bdbre first LT, reflecting a worse general clinical condition The progression of f*brosis m the second allografl was independent ot the rate of fibrosis progression in the first allograft. Donor age at first LT was statistically higher than donor age at second LT (p<O 000 l) (see Table). Conclusions: In pts with HCVrelated liver disease undergoing re-L1 for late graft loss the rapid rate of fibrosis progression in the first graft does not predict similar outcome after second LT. It is appropriate to consider re~tmnsp]amation Ic~r HCV recurrence aider LT. Our data corroborates that advanced age ot the donor appears as the most important predictor of rapid progression of fibrosis and graft loss in HCV-mfected patients undergoing LT.
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