Abstract
To the Editor. — In a secondary analysis of data from 2 randomized trials, Hewitt et al1 reached the conclusion that early treatment of acute pyelonephritis in infants and young children has no significant effect on the incidence of subsequent renal scarring. This conclusion was based, in part, on data from a clinical trial2 that enrolled children who had a first episode of febrile urinary tract infection (UTI) and met entry criteria for a “clinical diagnosis of acute pyelonephritis.” Importantly, one …
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