Treatment of pulmonary artery stump thrombosis after lobectomy: a case report and literature review.

Maria Wieteska-Miłek,Włodzimierz Kupis,Kinga Winiarczyk

doi:10.5603/arm.a2021.0010

Abstract

Lung cancer surgery is a well-known risk factor for venous thromboembolism. Thus, standard care involves the use of pharmacological and mechanical prophylaxis until discharge from the hospital. Pulmonary artery stump thrombosis (PAST) is a rare condition which can develop months to years after lung cancer surgery. This report describes a patient diagnosed with PAST and the decisions that were made regarding his treatment. A 67-year-old male was diagnosed with lung cancer due to shortness of breath, dry cough, hemoptysis, and typical chest computed tomography (CT) findings. He underwent right lower lobectomy and mediastinal lymphadenectomy by video-assisted thoracoscopic surgery. The procedure was complicated by the development of a right pleural empyema. After pleural drainage and an antibiotic regimen, he was discharged from the hospital with further improvement. A follow-up CT pulmonary angiography performed three months after lobectomy revealed thrombosis in the right lower lobar pulmonary artery stump. The patient had no symptoms. The attending physician decided to use anticoagulants. Consequently, the patient received low molecular-weight heparin subcutaneously for one month and a non-vitamin-K antagonist oral anticoagulant (NOAC) for the following 5 months. A CT scan performed after 3 months of anticoagulation showed complete resolution of stump thrombosis. Subsequent examinations showed no recurrence of either lung cancer or artery stump thrombosis and no anticoagulant-related bleeding. Pulmonary artery stump thrombosis can develop after lung cancer surgery. This complication is uncommon and the prognosis is favorable in most treated cases. However, thrombosis may progress, and pulmonary embolism or chronic thromboembolic pulmonary hypertension may develop. Decisions about instituting anticoagulation therapy and its duration are made on an individual basis after considering both the benefits and the potential risks.

Highlights

Lung cancer surgery is a well-known risk factor for venous thromboembolism
The prevalence of pulmonary artery stump thrombosis (PAST) after all types of lung cancer surgery collectively in retrospective analyses ranged from 1.9–5.7% [4, 5]
After being diagnosed with Pulmonary artery stump thrombosis (PAST), patients could ask their doctor about the possible complications and treatment options

Summary

Introduction

Lung cancer surgery is a well-known risk factor for venous thromboembolism. standard care involves the use of pharmacological and mechanical prophylaxis until discharge from the hospital. The risk of developing venous thromboembolism (VTE), including pulmonary embolism (PE) and/or deep vein thrombosis, after lung cancer surgery is approximately 2% (0.2–19%) [1], with the highest incidence within the first months after surgery [2]. The prevalence of pulmonary artery stump thrombosis (PAST) after all types of lung cancer surgery collectively in retrospective analyses ranged from 1.9–5.7% [4, 5].

Results

Conclusion