Abstract
Pediatric cutaneous lymphomas are a group of lymphoproliferative diseases with obvious heterogeneity, which are primarily derived from the skin. The classification is mainly based on the WHO-EORTC and WHO systems. The most common types of primary cutaneous lymphomas in children are cutaneous mature T-cell lymphomas (CTCL) and cutaneous mature B-cell lymphomas (CBCL) . Pediatric cutaneous lymphomas are rare, and their treatment approaches are mainly based on some case reports because of their clinical manifestations different from those of adults, few clinical trials and cautious medication. Treatments include topical drugs, phototherapy, radiotherapy, chemotherapy, surgery, stem cell transplantation and some new drugs. There are great differences in the therapeutic approaches and responses among various types of cutaneous lymphomas. Conservative treatment is effective in most childhood mycosis fungoides and other cutaneous lymphomas with inert biological features, while invasive cutaneous lymphomas still require chemotherapy and targeted therapies. Invasive cutaneous lymphomas occur more frequently in children than adults, so more attention should be paid to systematic assessment and follow-up observation. Key words: Lymphoma; Skin; Lymphoma, T-cell; Lymphoma, B-cell; Child; Therapeutic uses
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