Treatment of patients with arterial hypertension combined with chronic obstructive pulmonary disease

Abstract

Purpose: to evaluate the treatment of patients with arterial hypertension in combination with chronic obstructive pulmonary disease. Materials and methods. 60 patients with arterial hypertension (AH) of II–III degree (WHO classification) incombination with chronic obstructive pulmonary disease (COPD) of I–III degree (International program «Global Strategy for Diagnosis, Management and Prevention of COPD» GOLD, 2017), that is, 32 men and 28 women aged 30 to 45 years (mean age 45.3 ± 1.6 years), were examined in the Cardiology and Internal Medicine Departments, Hospital with the Scientific and Clinical Center of Cardiology. The age of the patients is from 20 to 56 years, the average age of the examined is 45.3±1.6 years. The patients were divided into two equal groups, comparable in terms of sex, age, severity of the underlying and concomitant pathology. The doses of bronchodilator therapy did not change during the study. As the main antihypertensive therapy, the patients of the 1st group were prescribed an ARB — losartan at a dose of 50 mg per day, the patients of the 2nd group were prescribed an ACE inhibitor — enalapril 10 mg per day. The patients continued to receive previously prescribed doses of antiplatelet agents, statins, hydrochlorothiazide at a dose of 12.5 mg per day.