Abstract
IntroductionOsteonecrosis of the femoral head is a progressive disease that leads to femoral head collapse and osteoarthritis. Our goal in treating osteonecrosis is to preserve, not to replace, the femoral head.Case presentationWe present the case of a patient with bilateral osteonecrosis of the femoral head treated with autologous cultured osteoblast injection.ConclusionAlthough our experience is limited to one patient, autologous cultured osteoblast transplantation appears to be effective for treating the osteonecrosis of femoral head.
Highlights
Osteonecrosis of the femoral head is a progressive disease that leads to femoral head collapse and osteoarthritis [1]
The left femoral head was treated by allograft immediately after core decompression, while the right side was treated by injection of autologous cultured osteoblasts for four weeks after the core decompression (Fig. 1C)
If cultured autologous cells are successfully used for this treatment, some problems related to bone graft techniques might be overcome, such as donor site morbidity in autografts [5,6] and immunological problems in allografts [7]
Summary
Osteonecrosis of the femoral head is a progressive disease that leads to femoral head collapse and osteoarthritis. The left femoral head was treated by allograft immediately after core decompression, while the right side was treated by injection of autologous cultured osteoblasts for four weeks after the core decompression (Fig. 1C).
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