TREATMENT OF ORAL BLEEDING IN A PATIENT WITH FANCONI ANEMIA: ASSOCIATION WITH LOCAL HEMOSTATIC AGENT AND MOUTHGUARD

Abstract

Fanconi anemia (FA) is a rare autosomal recessive genetic disorder, characterized by congenital malformations of certain organs, thrombocytopenia, and chronic anemia due to the progressive failure of bone marrow, with an elevated risk of infections and bleeding. A 24-year-old male patient with FA was referred to our clinic with a chief complaint of cheek biting and resultant significant bleeding. During clinical evaluation, a traumatic ulcer in the left buccal mucosa was observed with a massive blood clot formed inappropriately along with continuous bleeding. The patient's platelet count was 4000/mm3, indicating the need of a platelet transfusion prior the procedure. Suture and topic antifibrinolytic agent dressing and an ethylene vinyl acetate (EVA) mouthguard was installed with the sole purpose of reduction of local trauma. After 7 postoperative days, the oral lesion was almost completely healed without secondary bleeding. Fanconi anemia (FA) is a rare autosomal recessive genetic disorder, characterized by congenital malformations of certain organs, thrombocytopenia, and chronic anemia due to the progressive failure of bone marrow, with an elevated risk of infections and bleeding. A 24-year-old male patient with FA was referred to our clinic with a chief complaint of cheek biting and resultant significant bleeding. During clinical evaluation, a traumatic ulcer in the left buccal mucosa was observed with a massive blood clot formed inappropriately along with continuous bleeding. The patient's platelet count was 4000/mm3, indicating the need of a platelet transfusion prior the procedure. Suture and topic antifibrinolytic agent dressing and an ethylene vinyl acetate (EVA) mouthguard was installed with the sole purpose of reduction of local trauma. After 7 postoperative days, the oral lesion was almost completely healed without secondary bleeding.