Treatment of oesophageal Crohn's disease with infliximab.

Abstract

We read with interest the report by Naranjo-Rodriguez et al. [1] of a case with isolated oesophageal involvement of Crohn’s disease. The patient developed a long stricture with no response to endoscopic dilatations, and a surgical resection of the oesophagus was required. Pathological findings characteristic of Crohn’s disease were found in the surgical specimen. The authors mentioned the use of corticosteroids, ciclosporin and proton pump inhibitors as therapeutic options for oesophageal Crohn’s disease. We would like to add our experience of dealing with a patient who had Crohn’s disease and oesophageal involvement where the use of infliximab led to complete healing of the oesophageal lesions. We also review the literature on the use of infliximab in oesophageal Crohn’s disease.