Abstract
Microsurgical treatment is well established as the preferred strategy for definitive obliteration of middle cerebral artery (MCA) aneurysms. However, increasing reports on the feasibility and efficacy of endovascular treatment of MCA aneurysms in large case series suggest coiling as a viable alternative to microsurgery. This review provides a critical overview of the current literature regarding MCA aneurysm treatment, with the objective to clarify the available evidence of efficacy with microsurgical compared to endovascular treatment.
Highlights
Management strategies for intracranial aneurysms have changed dramatically over the past decades
Comparative treatment efficacy of an endovascular approach was evaluated in the multicenter randomized control trial (RCT) conducted by the International Subarachnoid Aneurysm Trial (ISAT) group in 2002, in which the early results at 1-year follow-up suggested superiority of coiling compared to clipping [7]
In response to ISAT, which resulted in the widespread adoption of a “coil first” policy, the Barrow Ruptured Aneurysm Trial (BRAT) was conducted in 2003 with the emphasis on treatment selection strategy in the presence of clinical equipoise
Summary
Management strategies for intracranial aneurysms have changed dramatically over the past decades. Comparative treatment efficacy of an endovascular approach was evaluated in the multicenter randomized control trial (RCT) conducted by the International Subarachnoid Aneurysm Trial (ISAT) group in 2002, in which the early results at 1-year follow-up suggested superiority of coiling compared to clipping [7]. In response to ISAT, which resulted in the widespread adoption of a “coil first” policy, the Barrow Ruptured Aneurysm Trial (BRAT) was conducted in 2003 with the emphasis on treatment selection strategy in the presence of clinical equipoise. Rinne et al explored anatomical and clinical features of MCA aneurysms in a Finnish population of 1314 consecutive patients According to their observations, 42.6 % of all aneurysm patients have at least one MCA aneurysm, in which 20.0 %
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
