Abstract
The use of repeated oral activated charcoal (ROAC) administration is reported in two patients who presented with acute meprobamate ingestions. Both patients had a measured meprobamate half-life of approximately 4.5 hours, the shortest reported in the literature. ROAC appears to be a safe, effective agent that may play a role in increasing the clearance of a number of agents from the systemic circulation. Further study in this area is needed.
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