Abstract
Liver cancer is an extraordinarily heterogeneous malignancy with relatively high mortality and increasing incidence rate among the so far identified cancers. Improvements in liver cancer therapy have been made in the past decades, but therapeutics against liver cancer are still limited. Traditional Mongolian Medicine, formed and developed by the Mongolian people to maintain health in the medical practice of fighting against diseases, has been recognized as one of the key components of the world healthcare system. Traditional Mongolian Medicine has been used to treat various malignancies, including liver cancer, for a long time in Asia and its advantages have become more and more apparent. Herein, this review made a comprehensive summary of Traditional Mongolian Medicine, including the ideas in the liver cancer treatment, sources of medicines or prescriptions, traditional applications, modern pharmacological research, chemical structure and mechanisms of several monomer compounds isolated from Traditional Mongolian Medicine, with a view to finding promising drugs against liver cancer and expanding the clinical application of Traditional Mongolian Medicine in liver cancer therapy.
Highlights
“Drug Standards of the Ministry of Health of the People’s Republic of China (Mongolian Medicines Volume)” [37] and other classic works. is prescription is composed of Calculus bovis, Dianthus superbus, trogopterus dung, Scabiosa comosa, costus root, herpetospermum seed, Angelica sinensis, Aristolochia manshuriensis, and Crocus sativus [38]
Honghua Qinggan 13 flavors (HHQG) is from the Four Medical Tantras and is called “gurigumu-13,” which is included in the “Pharmaceutical Standards of the Ministry of Health of the People’s Republic of China” (Mongolian Medicines Volume) [41]
Artemisia lavandulaefolia DC. is used in traditional Mongolian medicine as a perennial herb that is widely distributed in Inner Mongolia of China
Summary
With the development of Mongolian medicine, the experts of Mongolian medicine actively absorbed the knowledge of plant taxonomy, pharmacognosy, natural pharmaceutical chemistry, pharmacology, and other aspects and compiled a series of teaching materials and authoritative books with the support and organization of the government, such as “Mongolian Pharmacy,” “Encyclopedia of Mongolian Medicine,” “Prescription of Mongolian Medicine,” “Drug standard of the Ministry of health of the people’s Republic of China (Mongolian medicine volume),” and “Chinese Materia Medica Mongolian Medicine Volume.” ese modern Mongolian medicine books and standards have made important contributions to the modernization of Mongolian medicine and will benefit mankind Both Mongolian medicine and traditional Chinese medicine are traditional medicine, there are many differences in their sources and clinical uses [16, 17]. In the process of chemotherapy, Mongolian medicine can protect normal cells from chemotherapeutic/radiotherapeutic injuries, consolidate or enhance the effect of chemotherapy/radiotherapy, and prevent cancer metastasis and recurrence. is review introduces the ideas of Mongolian medicine in the treatment of liver cancer and the research progress of common clinical drugs (Tables 1 and 2.) and their possible mechanisms
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