Treatment of Infrarenal Abdominal Aortic Aneurysms With Oversized (36-mm) Zenith Endografts

Abstract

To evaluate the outcome of treating infrarenal abdominal aortic aneurysms with unfavorable necks using the 36-mm Zenith endograft. The indication for use of the 36-mm endograft for infrarenal aortic aneurysm was a minimum 20-mm-long sealing zone and a diameter >28 mm at any point but <34 mm, varying more than 3 mm in contour. A series of 67 patients (64 men; mean age 76.2 years, range 59.5 to 88.3) who had been treated with the 36-mm endografts between June 1999 and February 2004 were assessed for medium-term outcomes. The patients were identified from the device planning records. Follow-up was carried out using chart review and direct patient contact. The indication for use of the endograft was checked with the aneurysm neck profile from the original planning diagrams. Cause of death was ascertained from the treating clinician, the medical record, or the State Death Registry. Outcome endpoints were proximal type I and type III endoleaks, migration, sac size change, and death. The mean diameter of the sealing zone was 31.9+/-1.6 mm within the 20-mm segment from the lowest renal artery. Stent-graft delivery was achieved in all 67 patients. Two (3%) patients died within 30 days from non-graft-related cardiorespiratory causes. Proximal type I endoleaks were identified in 3 (4.5%) patients: 2 during deployment and another at 9 days. The mean follow-up period for the 65 patients who survived 30 days was 26.9+/-12.6 months (range 2-66). Migration occurred in 1 patient with development of a type III endoleak and sac reperfusion due to separation of the graft body from the bare anchor stent owing to suture breakage. Forty-seven patients were alive at the last review. The aneurysm sac had contracted or was unchanged in 45 (96%) cases. Minor enlargements of the sac were observed in 2 patients. The re-intervention rate was 16.4% (11 patients). There was 1 conversion to open repair to treat perigraft sepsis. The aneurysm- and procedure-related mortality was 4.5%; no patient experienced rupture. All-cause mortality was 29.9% (20/67). Large caliber endografts such as the Zenith 36-mm are an alternative option to open surgery or fenestrated endografting for some infrarenal aneurysms.