Abstract
Hypothyroidism, a deficiency of thyroid hormone usually caused by primary thyroid failure, is a common clinical problem. Levothyroxine therapy (LT4) is demonstrated to improve signs, symptoms, and biochemical abnormalities and improve life.[[1]] However, a recent online survey published by the American Thyroid Association (ATA) illustrates that 10%–15% of hypothyroid patients are not satisfied with their therapy, and the challenge facing practicing physicians is to investigate alternative methods of replacing thyroid hormone deficiency.[[2]]
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