Abstract
Cystic echinococcosis is a disease of animals and humans caused by the larval stage of of Echinococcus granulosus sensu lato and has a substantial public health impact globally. The condition is considered a neglected tropical disease (NTD) and neglected zoonotic disease (NZD), and prioritized by the World Health Organization (WHO) 1.Within the last 10 years, advancements have taken place in Echinococcus biology and genetics, including the delineation of new species within E.granulosus sensu lato (s.l.)2,3 and full sequencing of E. granulosus sensustricto. 2 Consequently, researchers are now provided with new tools to better understand parasite biology and host-parasite interactions, with the goal of opening new avenues for therapy 2. Echinococcus granulosus sensu stricto (s. s.) (G1-3) is responsible for the great majority of human CE worldwide (88.48%), has the most cosmopolitan distribution and is often associated with transmission via sheep as intermediate hosts.JMS 2016; 19(1):5-11
Highlights
Cystic echinococcosis is a disease of animals and humans caused by the larval stage of of Echinococcus granulosus sensu lato and has a substantial public health impact globally
The diagnosis and clinical management of cystic echinococcosis have evolved over decades in the absence of a systematic approach[11,12]
The first widely used ultrasound classification of hepatic cystic echinococcosis cysts has been proposed by Gharbi et al in 19815 and has been used in the following years as the basis for a number of other classifications
Summary
Tariq A Gojwari, M.D., Tahleel A Shera, M.D., Naseer A Choh, M.D., Feroze A Shaheen, M.D., Manjeet Singh, M.D., Irfan Robbani, M.D., Sheikh Reyaz, M.D. The accumulated knowledge based on singlecentre experiences and on the few clinical trials comparing at least some of these treatment modalities[12,16] supports a stage-specific approach to hepatic cystic echinococcosis[7,11]. The WHO-IWGE expert consensus for the diagnosis and treatment of echinococcosis in humans, issued in 2010, indicated several stage-specific options for the management of hepatic cystic echinococcosis, it acknowledged that the choice of treatment for individual patients depends on a number of variables, including cyst stage and other characteristics of the cyst, the patient, and the centre where the patient is visited. A structured cyst stage-specific approach to patient management has been recommended based on the WHO-International Working Group on Echinococcosis cyst classification scheme, which was officially adopted in 20107.
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