Abstract
In cases of severe hemorrhagic shock small volumes of hypertonic-hyperoncotic solutions (HHS) are efficient in restoring cardiovascular function immediately (1–3). While the macrocirculatory changes following infusion of HHS after hemorrhagic shock are well understood (4–6), little is known about the effects of this treatment on the central nervous system in particular in the presence of cerebral injury comprising deleted autoregulation and brain edema (7). We have, therefore, investigated the changes in oxygen supply of the brain in the presence of a cryogenic lesion after hemorrhagic shock and infusion of 7.2% NaCl/10% Dextran 60.
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