Treatment of gingival recession with coronally advanced flap combined with connective tissue graft/alloderm: A systematic review

Abstract

The purpose of this systematic review was to compare the efficacy of acellular dermal matrix (ADM) with coronally advanced flap (CAF) to connective tissue graft (CTG) with CAF in the treatment of localized Miller's Class I and II gingival recessions. Systematic review was limited to randomized clinical trials (RCTs) on the treatment of Miller Class I and II gingival recessions with at least 6 months of follow-up. Articles from January 1 1990 to June 2014 related to ADM were searched utilizing the MEDLINE database from the National Library of Medicine and through hand searches of reviews and recent journals. The primary outcome variable was root coverage (RC). A total of 248 Miller Class I and II gingival recessions in 143 patients from 10 RCTs were evaluated in this systematic review. Data collected by this study connote the following: There were no significant differences between ADM with CAF and CTG with CAF for recession coverage, and both procedures may be equally effective in clinical practice. Within the limitations of this study, it appears that ADM-based periodontal plastic surgery can be used successfully to treat gingival recession defects and to increase keratinized gingiva.