Abstract
Significant economic losses due to diarrhoea morbidity in newborn young animals lead to a decrease in the profitability of the sector in the structure of agricultural production. Therefore, the purpose of this study was to create and investigate the therapeutic effect of application of complex phytomineral preparation using local components: opoka of Taskala deposit and decoction of camelthorn (Alhagi maurorum) for treatment of diarrhoea in calves. The therapeutic effect of the preparation was studied in the conditions of dairy farm in Kyzylorda region on 5-7-day-old calves. The effect of the preparation was studied in a comparative aspect with an analogous preparation of imported production and the results obtained from healthy animals. Clinical, haematological, and biochemical methods of investigation were employed. The findings obtained suggest a high therapeutic effect of the created preparation. Its application allowed reducing the duration of the treatment period by 5-7 days compared to the imported preparation and restoring the positive dynamics of average daily gain as early as on the 5th day after the start of treatment. Haematological studies indicate stimulation of the immune system in animals that was manifested by a 14% increase in the count of lymphocytes and a 37% increase in the proteins of the γ-globulin fraction compared to healthy animals. These indices suggest an increase in the activity of the humoral part of the immune system in animals after treatment with the preparation. Another positive therapeutic effect of the preparation was observed in the protective effect on the liver of diseased animals. Despite the present effect of both preparations, the decrease in the activity of markers characterising hepatocyte destruction was higher with the Kazakh preparation. Thus, the created preparation is characterised by a higher therapeutic effect in comparison with the imported preparation and allow recommending it for treatment and prevention of diarrhoea in young animals
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